Novel 2D Graphic Representation of Protein Sequence and Its Application
نویسندگان
چکیده
In recent years, more and more researchers presented their graphic representations for protein sequence. Here, we present a new 2D graphic representation of protein sequence based on four physicochemical properties of 20 amino acids. By this graphic representation we define a distance calculation formula to quantificationally calculate the similarity degree of different protein sequences. Then we apply the proposed graphical curve and new distance in the similarity/dissimilarity comparison of 10 ND5 proteins and the protein sub-cellular localization prediction about two common test datasets, ZD98 and CL317. The results show the proposed method is easy and effective.
منابع مشابه
A Novel 2D Graphical Representation and its Application in the Similarities/Dissimilarities Analysis of Protein Sequences
Email: [email protected] Abstract: In this study, a novel 2D graphical representation of protein sequences is proposed based on the physicochemical feature pK2 of amino acids first and then, on the basis of the newly given 2D graphical representation, a new concept of feature appearance model is introduced to analyze the similarity/dissimilarity of protein sequences. Finally, Theoretical and sim...
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